BERKELEY – They scored early and kept adding on, with different players spraying hits to all parts of the ballpark as the innings ticked away.

The Bears put a shellacking on No. 3 Stanford on Saturday, an 18-2 rout that represents the Cal baseball team's most lopsided win over its rival in at least 16 years.

The run total was a season high as were the 20 hits. Five different players hit home runs and right-hander Jared Horn continued his dominant run with seven scoreless innings to win for the fifth time in his past six starts.

Perhaps most importantly, the Bears responded after a deflating 10-7 loss in Friday's series opener, playing sharply in all facets of the game and dominating a team that's been a consensus top-five squad for most of this season.

"For us to have a rough one yesterday and come back and play the way we did, that was outstanding," Cal head coach Mike Neu said. "It's good to see the way our guys came back and responded from a tough loss. I don't think we could have drew it up much better than we did today."

Cal (29-16, 14-9 Pac-12) gave up a 6-4 lead in the middle innings Friday, squandering a chance to break the game open in a bases-loaded situation and committing two errors that aided Stanford's cause.

On Saturday, they scored four in the first off Cardinal starter Will Matthiessen, with Andrew Vaughn, Max Flower and Darren Baker all contributing run-scoring doubles.

The Bears never looked back.

Cameron Eden went 3-for-3 with four RBI, Quentin Selma hit his third homer of the series and knocked in three and Flower homered and had three RBI of his own. Sam Wezniak, John Lagattuta and Hance Smith all went deep as well.

Wezniak was looking to rebound after a rough game Friday, and he complemented his ninth homer with a tumbling catch in shallow left field of Christian Robinson's pop fly in the eighth.

"It was a full-on complete team win," Wezniak said. "We did everything on all sides of the ball really well."

Horn (5-1) was terrific, blanking Stanford (36-9, 18-5) over seven innings, allowing just three hits and striking out six. The junior lowered his ERA from 2.03 to 1.80, second-best in the Pac-12.

Neu likened Horn's effort Saturday to his April 19 win over No. 1 UCLA, when the right-hander came out dealing one night after Cal suffered a walk-off loss.

"Jared over the last four or five weeks has been outstanding," Neu said. "No different today."

Research shows the Bears  hadn't beaten Stanford by such a wide margin since at least 2003.

The win marked Cal's fourth over a top-10 team this season. The previous three all came on the road – March 9 over No. 10 LSU, March 22 over No. 7 Oregon State and the April 19 win over the top-ranked Bruins.

Sunday's series finale begins at 12:05 p.m. as Cal goes for its first series victory over Stanford since 2014. The game will air live on the Pac-12 Network.